Phenyl isocyanate → 4-[[(Dimethylamino)methylene]amino]-3-pyridinol phenylcarbamate

HRID 361334

Reaktionsgleichung

Reaktionsgleichung von HRID 361334
[CH3:1][N:2]([CH:4]=[N:5][C:6]1[CH:11]=[CH:10][N:9]=[CH:8][C:7]=1[OH:12])[CH3:3].[C:13]1([N:19]=[C:20]=[O:21])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>O1CCCC1>[C:13]1([NH:19][C:20]([O:12][C:7]2[CH:8]=[N:9][CH:10]=[CH:11][C:6]=2[N:5]=[CH:4][N:2]([CH3:1])[CH3:3])=[O:21])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Komponenten

4

Edukt 2

HCID 7672Phenyl isocyanateHCID 153809294-[[(Dimethylamino)methylene]amino]-3-pyridinol

Produkt 1

HCID 677490644-[[(Dimethylamino)methylene]amino]-3-pyridinol phenylcarbamate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

To a warm solution of 4-[[(dimethylamino)methylene]amino]-3-pyridinol (3.0 g) in dry tetrahydrofuran (60 mL) was added phenyl isocyanate (2.05 mL). The reaction mixture was stirred at room temperature for 1.5 hours and filtered. The solid was washed with dry diethyl ether, air dried, and dried under high vacuum and refluxing ethanol for 4 hours to yield 4.19 g of solid, m.p. 151° C.

Aufarbeitung

  1. filtrationfiltered
  2. washThe solid was washed with dry diethyl ether, air
  3. customdried
  4. customdried under high vacuum
  5. temperaturerefluxing ethanol for 4 hours

Quellen und Nachweise

ORD-Eintrag
ord-5346322bd6644f4ba5dfc813f96a7685
Quelldatensatz
uspto-grants-1999_02
Patentnummer
US05866565

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