(Aminomethyl)phosphonic acid → Glyphosate

HRID 363808

Reaktionsgleichung

Reaktionsgleichung von HRID 363808
[NH2:1][CH2:2][P:3](=[O:6])([OH:5])[OH:4].O.[C:8]([OH:12])(=[O:11])[CH:9]=O>[Pd]>[NH2:1][CH2:2][P:3](=[O:4])([OH:6])[OH:5].[CH2:9]([NH:1][CH2:2][P:3]([OH:5])([OH:4])=[O:6])[C:8]([OH:12])=[O:11]

Komponenten

5

Edukt 2

HCID 14017(Aminomethyl)phosphonic acidHCID 15620607Glyoxylic acid, monohydrate

Produkt 2

HCID 3496GlyphosateHCID 14017(Aminomethyl)phosphonic acid

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 23938PalladiumKatalysator

Versuchsvorschrift

Aminomethylphosphonic acid was reductively alkylated with glyoxylic acid hydrate under catalytic hydrogenation conditions in the manner described in Example 2, except that the catalyst used was palladium metal (0.05 g), and the pH of the initial reaction mixture was 4.5. A 27% conversion of aminomethylphosphonic acid was obtained with a 93.7% selectivity to glyphosate.

Aufarbeitung

  1. customthe pH of the initial reaction mixture

Quellen und Nachweise

ORD-Eintrag
ord-6b0ffd800a764d7a9a88d4527dff1c5a
Quelldatensatz
uspto-grants-1999_02
Patentnummer
US05874612

Verknüpfte Notizen

Wird geladen…