N,N-Dimethyl-1,4-dioxaspiro[4.5]decan-8-amine → 4-(Dimethylamino)cyclohexan-1-one

HRID 365251Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 365251
C1O[C:4]2([CH2:9][CH2:8][CH:7]([N:10]([CH3:12])[CH3:11])[CH2:6][CH2:5]2)[O:3]C1>C(O)=O>[CH3:11][N:10]([CH3:12])[CH:7]1[CH2:8][CH2:9][C:4](=[O:3])[CH2:5][CH2:6]1

Komponenten

3

Edukt 1

HCID 361167N,N-Dimethyl-1,4-dioxaspiro[4.5]decan-8-amine

Produkt 1

HCID 103745454-(Dimethylamino)cyclohexan-1-oneAusbeute 100 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 284Formic AcidLösungsmittel

Versuchsvorschrift

4.96 gm (26.8 mMol) 4-dimethylamino-1-cyclohexanone ethylene ketal were dissolved in 50 mL formic acid and the solution stirred at reflux for 18 hours. The reaction mixture was then cooled to ambient and the volatiles removed under reduced pressure to give 3.78 gm (100%) of the title compound.

Aufarbeitung

  1. temperatureat reflux for 18 hours
  2. temperatureThe reaction mixture was then cooled to ambient and the volatiles
  3. customremoved under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-3e59ea4ef37c4843a7b851f41bcc0878
Quelldatensatz
uspto-grants-2000_10
Patentnummer
US06126932

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