Chlorotrimethylsilane → 2-Chloro-n-ethyl-6-(trimethylsilyl)benzamide

Reaktionsgleichung

[CH2:1]([NH:3][C:4](=[O:12])[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[Cl:11])[CH3:2].[CH3:13][Si:14](Cl)([CH3:16])[CH3:15]>>[Cl:11][C:6]1[CH:7]=[CH:8][CH:9]=[C:10]([Si:14]([CH3:16])([CH3:15])[CH3:13])[C:5]=1[C:4]([NH:3][CH2:1][CH3:2])=[O:12]

Komponenten

Edukt 2

HCID 6397Chlorotrimethylsilane

HCID 3479622-chloro-N-ethylbenzamide

Produkt 1

HCID 186303792-Chloro-n-ethyl-6-(trimethylsilyl)benzamide

Versuchsvorschrift

The compound of Example f (2.2 g, 0.012 mol) was reacted with TMSCl (3.91 g, 0.036 mol) using General Method A. The title compound was recrystallized from ether/hexanes as a solid. m.p. 105-107° C.

Aufarbeitung

customThe title compound was recrystallized from ether/hexanes as a solid

Quellen und Nachweise

ORD-Eintrag: ord-26982034b01c4721a756e22a17cbba3f
Quelldatensatz: uspto-grants-2000_10
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US06133252

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