HCID 3824885, Verbindung → 7-Amino-3,3-dimethyl-3,4-dihydroquinoxalin-2(1H)-one

HRID 36862Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 36862
[CH3:1][C:2]1([CH3:16])[C:11](=[O:12])[NH:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([N+:13]([O-])=O)[CH:8]=2)[NH:3]1>CO.[Pd]>[NH2:13][C:7]1[CH:8]=[C:9]2[C:4](=[CH:5][CH:6]=1)[NH:3][C:2]([CH3:1])([CH3:16])[C:11](=[O:12])[NH:10]2

Komponenten

4

Edukt 1

HCID 3824885HCID 3824885, Verbindung

Produkt 1

HCID 152257137-Amino-3,3-dimethyl-3,4-dihydroquinoxalin-2(1H)-one

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

A solution of 1,2-dihydro-2,2-dimethyl-6-nitro-3-(4H)-quinoxalinone (663 mg, 3 mmol) in CH3OH (10 ml) is hydrogenated with 50 psi H2 (g) at room temperature in the presence of a catalyst of 10% by weight palladium on charcoal (50 mg). After the starting material is consumed, the solution is filtered and concentrated in vacuo to yield 6-amino-1,2-dihydro-2,2-dimethyl-3-(4H)-quinoxalinone.

Aufarbeitung

  1. customAfter the starting material is consumed
  2. filtrationthe solution is filtered
  3. concentrationconcentrated in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-af8e15160ac846cab0fac872a1b545db
Quelldatensatz
uspto-grants-1995_05
Patentnummer
US05418234

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