Morpholine → HCID 23288680, Verbindung
Reaktionsgleichung
[OH:1][CH:2]([CH2:35][OH:36])[CH2:3][O:4][C:5]1[CH:6]=[C:7]([CH:11]=[C:12]([NH:23][S:24]([C:27]2[CH:32]=[CH:31][C:30]([S:33][CH3:34])=[CH:29][CH:28]=2)(=[O:26])=[O:25])[C:13]=1[O:14][C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([O:21][CH3:22])[CH:16]=1)[C:8](O)=[O:9].[NH:37]1[CH2:42][CH2:41][O:40][CH2:39][CH2:38]1>>[OH:1][CH:2]([CH2:35][OH:36])[CH2:3][O:4][C:5]1[C:13]([O:14][C:15]2[CH:20]=[CH:19][CH:18]=[C:17]([O:21][CH3:22])[CH:16]=2)=[C:12]([NH:23][S:24]([C:27]2[CH:32]=[CH:31][C:30]([S:33][CH3:34])=[CH:29][CH:28]=2)(=[O:25])=[O:26])[CH:11]=[C:7]([C:8]([N:37]2[CH2:42][CH2:41][O:40][CH2:39][CH2:38]2)=[O:9])[CH:6]=1Komponenten
3
Versuchsvorschrift
In analogy to Example 121, by coupling 3-(2,3-dihydroxy-propoxy)-4-(3-methoxy-phenoxy)-5-(4-methylsulphanyl-benzenesulphonylamino)-benzoic acid with morpholine there was obtained N-[3-(2,3-dihydroxy-propoxy)-2-(3-methoxy-phenoxy)-5-(morpholine-4-carbonyl)-phenyl]-4 methylsulphanyl-benzenesulphonamide as a white foam.
Quellen und Nachweise
- ORD-Eintrag
- ord-2ec52447d8764019985c34dbf94324bf
- Quelldatensatz
- uspto-grants-2000_10
- Patentnummer
- US06133442