Acetic Anhydride → (3,4,8-trimethyl-2-oxochromen-7-yl) acetate

HRID 368785Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 368785
[OH:1][C:2]1[C:11]([CH3:12])=[C:10]2[C:5]([C:6]([CH3:15])=[C:7]([CH3:14])[C:8](=[O:13])[O:9]2)=[CH:4][CH:3]=1.[C:16](OC(=O)C)(=[O:18])[CH3:17]>>[C:16]([O:1][C:2]1[C:11]([CH3:12])=[C:10]2[C:5]([C:6]([CH3:15])=[C:7]([CH3:14])[C:8](=[O:13])[O:9]2)=[CH:4][CH:3]=1)(=[O:18])[CH3:17]

Komponenten

3

Edukt 2

HCID 7918Acetic AnhydrideHCID 53971957-Hydroxy-3,4,8-trimethylcoumarin

Produkt 1

HCID 854734(3,4,8-trimethyl-2-oxochromen-7-yl) acetate

Versuchsvorschrift

A solution of 7-hydroxy-3,4,8-trimethylcoumarin (5.19 g, 25.4 mmol) was refluxed in acetic anhydride (10 mL) for 1.5 hours. The solution was slowly poured into ice water (200 mL) and the resulting solid was filtered, then rinsed with water to yield 7-acetoxy-3,4,8-trimethylcoumarin, a beige solid (6.22 g, 99.5%). 1H NMR (CDCl3): δ 7.47 (d, J=8.6 Hz, 1H), 7.00 (d, J=8.7 Hz, 1H), 2.40 (s, 3H), 2.37 (s, 3H), 2.29 (s, 3H), 2.22 (s, 3H).

Aufarbeitung

  1. filtrationthe resulting solid was filtered
  2. washrinsed with water

Quellen und Nachweise

ORD-Eintrag
ord-17b351b7ffad493b8a0726e9a548485b
Quelldatensatz
uspto-grants-2000_10
Patentnummer
US06133460

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