Benzamide → 4'-Nitrobenzanilide

HRID 369491Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 369491
[C:1]([NH2:9])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N+:10]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)([O-:12])=[O:11]>>[N+:10]([C:13]1[CH:18]=[CH:17][C:16]([NH:9][C:1](=[O:8])[C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[CH:15][CH:14]=1)([O-:12])=[O:11]

Komponenten

3

Edukt 2

HCID 2331BenzamideHCID 7416Nitrobenzene

Produkt 1

HCID 769304'-Nitrobenzanilide

Versuchsvorschrift

According to the recently released paper in line with the direct manufacture of amide compound formed by the NASH reaction, it is reported that benzamide is reacted with nitrobenzene in the presence of TMA(OH) to isolate N-(4-nitrophenyl)benzamide, a relatively stable intermediate, and then methanol and ammonia are added to the mixture and reacted under a pressure reactor to prepare 4-nitroaniline as a final product, while regenerating benzamide (J. Org. Chem., 1993, 58(24), 6883-8; WO No. 93/24447).

Aufarbeitung

  1. customformed by the NASH reaction, it

Quellen und Nachweise

ORD-Eintrag
ord-c2591c8af2394bc5a21b9b9ce58b6387
Quelldatensatz
uspto-grants-2000_10
Patentnummer
US06137010

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