Ammonium Hydroxide → HCID 21584299, Verbindung

HRID 369956Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 369956
[CH2:1]1[CH:10]2[N:5]([C:6](=[O:15])[C:7]3[CH:14]=[CH:13][CH:12]=[CH:11][C:8]=3[CH2:9]2)[CH2:4][CH2:3][CH2:2]1.[N+:16]([O-])([O-:18])=[O:17].[K+].[OH-].[NH4+]>S(=O)(=O)(O)O>[N+:16]([C:13]1[CH:12]=[CH:11][C:8]2[CH2:9][CH:10]3[N:5]([C:6](=[O:15])[C:7]=2[CH:14]=1)[CH2:4][CH2:3][CH2:2][CH2:1]3)([O-:18])=[O:17]

Komponenten

5

Edukt 3

HCID 14923Ammonium HydroxideHCID 24434Potassium NitrateHCID 27527926H-Benzo[b]quinolizin-6-one, 1,2,3,4,11,11a-hexahydro-

Produkt 1

HCID 21584299HCID 21584299, VerbindungAusbeute 92 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1118Sulfuric AcidLösungsmittel

Versuchsvorschrift

1,3,4,6,11,11a-Hexahydro-2H-benzo[b]quinolizin-6-one (3.78 g, 18.7 mmol) was dissolved in concentrated sulfuric acid (50 ml) at 0° C., potassium nitrate (2.02 g, 20 mmol) was added and the reaction mixture was stirred overnight. The reaction mixture was poured onto ice (200 g) and was partially neutralized with concentrated ammonium hydroxide. The precipitate was collected and air-dried to give the title compound as a yellow solid (4.22 g, 92%), m.p. 137-42° C.

Aufarbeitung

  1. additionThe reaction mixture was poured onto ice (200 g)
  2. customThe precipitate was collected
  3. customair-dried

Quellen und Nachweise

ORD-Eintrag
ord-0bae4172384c471681c83b9d4bcfa88f
Quelldatensatz
uspto-grants-2000_10
Patentnummer
US06140322

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