Ethanol → 4-Hydrazinyl-1-methyl-1H-pyrazolo[3,4-d]pyrimidine
Reaktionsgleichung
Cl[C:2]1[N:7]=[CH:6][N:5]=[C:4]2[NH:8][N:9]=[CH:10][C:3]=12.O.[NH2:12][NH2:13].[CH2:14](O)C>>[NH:12]([C:2]1[N:7]=[CH:6][N:5]=[C:4]2[N:8]([CH3:14])[N:9]=[CH:10][C:3]=12)[NH2:13]Komponenten
4
Versuchsvorschrift
50 g. of 4-chloropyrazolo[3,4-d]pyrimidine are dissolved in 700 ml. of absolute ethanol and 25 g. of hydrazine hydrate in 100 ml. of ethanol are slowly added dropwise with stirring. This is stirred for 13 hours at room temperature and the product formed is then filtered under suction, water is added and the product, 4-hydrazino-1-methylpyrazolo[3,4-d]pyrimidine, is crystallized from dimethylformamide as yellowish crystals, m.p. 231°.
Aufarbeitung
- stirringThis is stirred for 13 hours at room temperature
- customthe product formed
- filtrationis then filtered under suction, water
- additionis added
- customthe product, 4-hydrazino-1-methylpyrazolo[3,4-d]pyrimidine, is crystallized from dimethylformamide as yellowish crystals, m.p. 231°
Quellen und Nachweise
- ORD-Eintrag
- ord-a270fd47da1e47c0978cfde1f3230638
- Quelldatensatz
- uspto-grants-1978_05
- Patentnummer
- US04087423
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