Dimethylformamide → HCID 19811955, Verbindung

HRID 373144Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 373144
[SH:1][C:2]1[O:3][C:4]([C:7]2[O:11][C:10]([N:12]([CH3:14])[CH3:13])=[N:9][N:8]=2)=[N:5][N:6]=1.O1CCOCC1.CN(C)C=O.Br[CH2:27][CH2:28][C:29]([F:33])=[C:30]([F:32])[F:31]>O>[F:33][C:29](=[C:30]([F:32])[F:31])[CH2:28][CH2:27][S:1][C:2]1[O:3][C:4]([C:7]2[O:11][C:10]([N:12]([CH3:14])[CH3:13])=[N:9][N:8]=2)=[N:5][N:6]=1

Komponenten

6

Edukt 4

HCID 6228DimethylformamideHCID 312751,4-DioxaneHCID 663334-Bromo-1,1,2-trifluorobut-1-eneHCID 178483107HCID 178483107, Verbindung

Produkt 1

HCID 19811955HCID 19811955, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

4.26 g of 2-mercapto-5-(2-dimethylamino-1,3,4-oxadiazol-5-yl)-1,3,4-oxadiazole according to Example H2 are initially introduced into 40 ml of dioxane and stirred with 2.24 g of potassium t-butylate. 4 ml of dimethylformamide and then 4.2 g of 4-bromo-1,1,2-trifluorobut-1-ene are added and the mixture is stirred overnight at room temperature. The mixture is poured into water and the crystals are filtered off with suction. After drying and stirring with ether, 4.6 g of the title compound of melting point 87°-90° C. are obtained.

Aufarbeitung

  1. filtrationthe crystals are filtered off with suction
  2. customAfter drying
  3. stirringstirring with ether, 4.6 g of the title compound of melting point 87°-90° C.
  4. customare obtained

Quellen und Nachweise

ORD-Eintrag
ord-cb0458332f62444597fd8cc0e25ef86f
Quelldatensatz
uspto-grants-1992_11
Patentnummer
US05162349

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