HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Cyclohexene → 9-Ethyl-4-[(1-methylpiperidin-4-yl)methylamino]imidazo[5,1-h]pteridin-6(5H)-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Cyclohexene | HCID 8079 | — |
| Edukt | 4,6-Dichloro-5-nitropyrimidine | HCID 20312 | — |
| Edukt | 2-Ethylimidazole | HCID 66130 | — |
| Edukt | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Edukt | 1-Methyl-4-(methylamino)piperidine | HCID 566323 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 9-Ethyl-4-[(1-methylpiperidin-4-yl)methylamino]imidazo[5,1-h]pteridin-6(5H)-one | HCID 70270934 | — |
Reaktionsschritte
Prepared by treatment of 4,6-dichloro-5-nitropyrimidine with 1-methyl-4-(methylamino)piperidine followed by reaction with 2-ethylimidazole, reduction with palladium on carbon and cyclohexene in refluxing ethanol, and cyclization with carbonyidiimidazole.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06025489 |
| Quelldatensatz | uspto-grants-2000_02 |
| ORD ID | ord-3212f7b590b4430483b6c6024c3e6bfd |
| Quellennotiz | uspto-grants-2000_02 |