Tetrahydrofuran → 2-Methoxy-4,5-dimethylaniline

HRID 377916Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 377916
O1CCCC1.[CH3:6][C:7]1[C:12]([CH3:13])=[CH:11][C:10]([O:14][CH3:15])=[C:9]([N+:16]([O-])=O)[CH:8]=1>[Pd].C(O)C>[CH3:13][C:12]1[C:7]([CH3:6])=[CH:8][C:9]([NH2:16])=[C:10]([O:14][CH3:15])[CH:11]=1

Komponenten

5

Edukt 2

HCID 8028TetrahydrofuranHCID 193571651-Methoxy-4,5-dimethyl-2-nitrobenzene

Produkt 1

HCID 193571402-Methoxy-4,5-dimethylanilineAusbeute 82 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

Tetrahydrofuran(100 ml) and ethanol(40 ml) were added into 4,5-dimethyl-2-nitroanisole(7.80 g, 0.043 mol) and then added 10% Pd/activated carbon(0.57 g) slowly, hydrogenated for 5 hrs. The reaction was completed by the same way with the above and the resulting product was purified by column chromatography to obtain the titled compound.

Aufarbeitung

  1. customwas purified by column chromatography

Quellen und Nachweise

ORD-Eintrag
ord-4c9f20c9fc284dd990bb3a0f2b887d33
Quelldatensatz
uspto-grants-2000_02
Patentnummer
US06028195

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