Dichloromethane → Phenyl N-(4,5-dimethyl-2-methoxyphenyl)thiocarbamate

HRID 377924Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 377924
C[C:2]1[C:3]([O:10][CH3:11])=[C:4]([CH:6]=[CH:7][C:8]=1[CH3:9])[NH2:5].[CH2:12](Cl)Cl.[CH:15]1[CH:20]=[CH:19][C:18]([O:21][C:22](Cl)=[S:23])=[CH:17][CH:16]=1>O>[CH3:9][C:8]1[C:7]([CH3:12])=[CH:6][C:4]([NH:5][C:22](=[S:23])[O:21][C:18]2[CH:19]=[CH:20][CH:15]=[CH:16][CH:17]=2)=[C:3]([O:10][CH3:11])[CH:2]=1

Komponenten

5

Edukt 3

HCID 6344DichloromethaneHCID 70498Phenyl thioxochloroformateHCID 178964772-Methoxy-3,4-dimethylaniline

Produkt 1

HCID 53857756Phenyl N-(4,5-dimethyl-2-methoxyphenyl)thiocarbamateAusbeute 92 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

To 3,4-dimethyl-2-methoxyaniline(4.50 g, 0.03 mol), methylene chloride(100 ml) was added and then phenyl chlorothionoformate(5.16 g, 0.03 mol) was added slowly. The resulting mixture was stirred for 2 hours, and thereto water(150 ml) was added. The resulting mixture was extracted with methylene chloride and purified by column chromatography to obtain the titled compound.

Aufarbeitung

  1. extractionThe resulting mixture was extracted with methylene chloride
  2. custompurified by column chromatography

Quellen und Nachweise

ORD-Eintrag
ord-4ed0aabd626a4eeeb2ae2dba8c03d4fc
Quelldatensatz
uspto-grants-2000_02
Patentnummer
US06028195

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