Sodium Hydroxide → 2-(Propylthio)pyrimidine-4,6-diol

HRID 378841

Reaktionsgleichung

Reaktionsgleichung von HRID 378841
[CH2:1](I)[CH2:2][CH3:3].[OH:5][C:6]1[CH:11]=[C:10]([OH:12])[N:9]=[C:8]([SH:13])[N:7]=1.[OH-].[Na+]>O>[OH:5][C:6]1[CH:11]=[C:10]([OH:12])[N:9]=[C:8]([S:13][CH2:1][CH2:2][CH3:3])[N:7]=1

Komponenten

5

Edukt 3

HCID 14798Sodium HydroxideHCID 336431-IodopropaneHCID 178516656HCID 178516656, Verbindung

Produkt 1

HCID 1784608102-(Propylthio)pyrimidine-4,6-diol

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

Propyl iodide (136 ml) was added to a suspension of 4,6-dihydroxy-2-mercaptopyrimidine (200 g) in water (800 ml), containing sodium hydroxide (55.6 g). The reaction mixture was stirred for 2 weeks then concentrated to half volume, 2N hydrochloric acid was added and the subtitle compound was isolated by filtration (167 g).

Aufarbeitung

  1. concentrationthen concentrated to half volume, 2N hydrochloric acid
  2. additionwas added

Quellen und Nachweise

ORD-Eintrag
ord-6e83b0f2d6c14146a36cb58912dd272d
Quelldatensatz
uspto-grants-2001_10
Patentnummer
US06297232B1

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