Lactide → Poliglecaprone

HRID 379496

Reaktionsgleichung

Reaktionsgleichung von HRID 379496
[CH2:1]1[O:8][C:6](=[O:7])[CH2:5][O:4][C:2]1=[O:3].[C:9]1(=[O:16])[O:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1.CCCCC(C([O-])=O)CC.CCCCC(C([O-])=O)CC.[Sn+2].C(O)CCCCCCCCC.CC1OC(=O)C(C)OC1=O>>[C:9]1(=[O:16])[O:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1.[CH2:1]1[O:8][C:6](=[O:7])[CH2:5][O:4][C:2]1=[O:3]

Komponenten

6

Edukt 5

HCID 7272LactideHCID 81741-DecanolHCID 93182-ethylhexanoic acid tin(II) saltHCID 10401epsilon-CAPROLACTONEHCID 65432Glycolide2×

Produkt 1

HCID 65431Poliglecaprone

Reaktionsbedingungen

Temperatur
170 °C

Versuchsvorschrift

Glycolide (0.13 moles) was mixed with ε-caprolactone (1.18) and a catalytic amount of stannous octoate (0.262 mole) and 1-decanol (3.275 mole). The system was heated to 170° C. and was stirred at this temperature for 30 minutes. The reaction was then cooled to 120° C. Glycolide (0.65 moles) and dl-lactide (0.52 moles) were added to the prepolymer. After melting the second charge, the system was heated to 170° C. and was stirred at this temperature for 6.5 hours. At the conclusion of the reaction, the unreacted monomer was removed by heating at 130° C. under reduced pressure for 1.5 hours. The resulting polymer was characterized by DSC (for Tm), solution viscosity (for molecular dimensions), IR and NMR (for chemical composition).

Aufarbeitung

  1. temperatureThe reaction was then cooled to 120° C
  2. temperaturethe system was heated to 170° C.
  3. stirringwas stirred at this temperature for 6.5 hours
  4. customAt the conclusion of the reaction
  5. customthe unreacted monomer was removed
  6. temperatureby heating at 130° C. under reduced pressure for 1.5 hours

Quellen und Nachweise

ORD-Eintrag
ord-1c558c26d9dd4b188c9a0b7c258b08d4
Quelldatensatz
uspto-grants-2001_10
Patentnummer
US06299631B1

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