HCID 12545264, Verbindung → N~1~-([1,1'-Biphenyl]-2-yl)benzene-1,2-diamine

HRID 383214Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 383214
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH:10][C:11]1[C:12]([C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[CH:13][CH:14]=[CH:15][CH:16]=1)([O-])=O.[H][H]>[Pd].C(O)C>[C:12]1([C:17]2[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=2)[CH:13]=[CH:14][CH:15]=[CH:16][C:11]=1[NH:10][C:5]1[C:4]([NH2:1])=[CH:9][CH:8]=[CH:7][CH:6]=1

Komponenten

5

Edukt 2

HCID 12545264HCID 12545264, VerbindungHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 13989156N~1~-([1,1'-Biphenyl]-2-yl)benzene-1,2-diamine

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

N-(2-nitrophenyl)biphenyl-2-amine (19.69 g, 67.8 mmol), 10% palladium on carbon (0.29 g, 0.27 mmol), and 150 mL of ethanol was added to a Parr hydrogenator bottle. The mixture was hydrogenated on a Parr hydrogenator until no more hydrogen was taken up by the solution. The solution was filtered through Celite to remove the catalyst, Celite was washed with dichloromethane, the filtrate was evaporated to yield a brown oil, 14.8 g (84%). The product was used for the next step without further purification.

Aufarbeitung

  1. filtrationThe solution was filtered through Celite
  2. customto remove the catalyst, Celite
  3. washwas washed with dichloromethane
  4. customthe filtrate was evaporated
  5. customto yield a brown oil, 14.8 g (84%)
  6. customThe product was used for the next step without further purification

Quellen und Nachweise

ORD-Eintrag
ord-8fa2ac664396495a8847c2a25ca89096
Quelldatensatz
uspto-grants-2013_02
Patentnummer
US08367223B2

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