HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-(5-nitro-2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)acetamide → N-(5-amino-2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)acetamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | N-(5-nitro-2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)acetamide | HCID 58098809 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | N-(5-amino-2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)acetamide | HCID 58098633 | 98,4% |
Reaktionsschritte
To a solution of N-(5-nitro-2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)acetamide (430 mg) in EtOH (10 mL) was added Pd/C (200 mg) and was charged with H2 (1 atm). After stirring for 3 h, Pd/C was removed by filtration and the filtrate was concentrated to give N-(5-amino-2-(2-(pyrrolidin-1-yl)ethoxy)phenyl)acetamide (380 mg).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08367689B2 |
| Quelldatensatz | uspto-grants-2013_02 |
| ORD ID | ord-d1633ed141fa4999a8ebff19c862db2f |
| Quellennotiz | uspto-grants-2013_02 |