Ethanol → 3-[2,5-Dioxo-4-[(2-propenyloxy)methyl]imidazolidin-4-yl]benzonitrile

HRID 389886Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 389886
[CH2:1]([O:4][CH2:5][C:6]([C:8]1[CH:15]=[CH:14][CH:13]=[CH:12][C:9]=1C#N)=O)[CH:2]=[CH2:3].O.[C-:17]#[N:18].[K+].[C:20](=[O:23])([O-])[O-].[NH4+:24].[NH4+:25].C[CH2:27][OH:28]>>[O:28]=[C:27]1[NH:25][C:6]([C:8]2[CH:9]=[C:12]([CH:13]=[CH:14][CH:15]=2)[C:17]#[N:18])([CH2:5][O:4][CH2:1][CH:2]=[CH2:3])[C:20](=[O:23])[NH:24]1

Komponenten

6

Edukt 5

HCID 702EthanolHCID 962WaterHCID 9032Potassium CyanideHCID 517111Ammonium CarbonateHCID 86641460(2-(2-Propenyloxy)acetyl]benzonitrile

Produkt 1

HCID 671310093-[2,5-Dioxo-4-[(2-propenyloxy)methyl]imidazolidin-4-yl]benzonitrile

Reaktionsbedingungen

Temperatur
55 °C

Versuchsvorschrift

To a solution of 450 mg of 3-[(2-(2-propenyloxy)acetyl]benzonitrile (in EtOH (5 mL) and water (5 mL) 291 mg of potassium cyanide and ammonium carbonate are added. The mixture is refluxed one night at 55° C. The mixture is extracted with ethyl acetate, dried over magnesium sulfate and concentrated under vacuum to give the desired compound.

Aufarbeitung

  1. extractionThe mixture is extracted with ethyl acetate
  2. dry with materialdried over magnesium sulfate
  3. concentrationconcentrated under vacuum

Quellen und Nachweise

ORD-Eintrag
ord-39ff7f05feeb4343b34cfb265185d649
Quelldatensatz
uspto-grants-2013_02
Patentnummer
US08383608B2

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