Oxalyl chloride → Dimethyl-1,3-oxazole-5-carbonyl chloride

HRID 391997Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 391997
[CH3:1][C:2]1[O:3][C:4]([C:8]([OH:10])=O)=[C:5]([CH3:7])[N:6]=1.C(Cl)(=O)C([Cl:14])=O>C(Cl)Cl>[CH3:1][C:2]1[O:3][C:4]([C:8]([Cl:14])=[O:10])=[C:5]([CH3:7])[N:6]=1

Komponenten

4

Edukt 2

HCID 65578Oxalyl chlorideHCID 1132979Dimethyl-1,3-oxazole-5-carboxylic acid

Produkt 1

HCID 12336332Dimethyl-1,3-oxazole-5-carbonyl chloride

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

To a stirring solution of 2,4-dimethyl-oxazole-5-carboxylic acid (30 mg) in DCM (2.0 mL), oxalyl chloride (3.0 eq) was added at room temperature. The reaction mixture was stirred for 30 minutes. Solvents were evaporated and dried under vaccuo to afford 2,4-dimethyl-oxazole-5-carbonyl chloride.

Aufarbeitung

  1. customSolvents were evaporated
  2. customdried under vaccuo

Quellen und Nachweise

ORD-Eintrag
ord-326750fd2a7e4eabb6511a9907fdbeda
Quelldatensatz
uspto-grants-2013_02
Patentnummer
US08383644B2

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