Acetic Anhydride → HCID 86759544, Verbindung

Reaktionsgleichung

[F:1][C:2]([F:12])([F:11])[C:3](=[O:10])[CH2:4][C:5](=[O:9])[CH:6]([CH3:8])[CH3:7].[CH:13]([O-])([O-])[O:14][CH2:15][CH3:16].C(OC(=O)C)(=O)C>>[CH2:15]([O:14][CH:13]=[C:4]([C:5](=[O:9])[CH:6]([CH3:8])[CH3:7])[C:3](=[O:10])[C:2]([F:11])([F:12])[F:1])[CH3:16]

Komponenten

Edukt 3

HCID 7918Acetic Anhydride

HCID 1601912,4-Hexanedione, 1,1,1-trifluoro-5-methyl-

HCID 53630039Ethylorthoformate

Produkt 1

HCID 86759544HCID 86759544, VerbindungAusbeute 67 %

Versuchsvorschrift

A mixture comprising 213 g (1.17 mol) of 1,1,1-trifluoro-5-methyl-2,4-hexanedione, 242 g (1.64 mol) of ethyl orthoformate and 166 g (1.63 mol) of acetic anhydride, was heated and refluxed for 6 hours. The solvent was distilled off under reduced pressure to obtain 146 g (yield: 67%) of 3-ethoxymethylene-1,1,1-trifluoro-5-methyl-2,4-hexanedione.