Acetyl chloride → Ethanone, 1-(4-octylphenyl)-

HRID 395940

Reaktionsgleichung

Reaktionsgleichung von HRID 395940
[Cl-].[Al+3].[Cl-].[Cl-].[CH2:5]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[C:19](Cl)(=[O:21])[CH3:20]>ClC(Cl)C>[CH2:5]([C:13]1[CH:14]=[CH:15][C:16]([C:19](=[O:21])[CH3:20])=[CH:17][CH:18]=1)[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

Komponenten

5

Edukt 3

HCID 6367Acetyl chlorideHCID 16607OctylbenzeneHCID 6451240Aluminum(III) Chloride

Produkt 1

HCID 66344Ethanone, 1-(4-octylphenyl)-

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 63651,1-DichloroethaneLösungsmittel

Versuchsvorschrift

Aluminum chloride (22.6 g) is suspended in dichloroethane (500 ml) and octylbenzene (16) (21.5 g) is added at room temperature. To the mixture is added acetyl chloride (8.87 g) under ice-cooling. The mixture is stirred at room temperature overnight. The reaction mixture is poured into ice water and extracted with ether. The organic layer is washed with brine and dried over sodium sulfate. The solvent is evaporated to give 4′-octylacetophenone (18′) as a colorless oil.

Aufarbeitung

  1. temperaturecooling
  2. extractionextracted with ether
  3. washThe organic layer is washed with brine
  4. dry with materialdried over sodium sulfate
  5. customThe solvent is evaporated

Quellen und Nachweise

ORD-Eintrag
ord-f0335febdb6e4fc9a41e2e6dafd45797
Quelldatensatz
uspto-grants-2003_08
Patentnummer
US06605744B2

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