Piperazine → HCID 131718840, Verbindung

HRID 399733

Reaktionsgleichung

Reaktionsgleichung von HRID 399733
[C:1]([NH:4][C@H:5]([C:18]([OH:20])=[O:19])[CH2:6][S:7][S:8][CH2:9][C@H:10]([NH:14][C:15](=[O:17])[CH3:16])[C:11]([OH:13])=[O:12])(=[O:3])[CH3:2].[NH:21]1[CH2:26][CH2:25][NH:24][CH2:23][CH2:22]1>O>[NH2+:21]1[CH2:26][CH2:25][NH:24][CH2:23][CH2:22]1.[C:15]([NH:14][C@H:10]([C:11]([O-:13])=[O:12])[CH2:9][S:8][S:7][CH2:6][C@H:5]([NH:4][C:1](=[O:3])[CH3:2])[C:18]([O-:20])=[O:19])(=[O:17])[CH3:16]

Komponenten

4

Edukt 2

HCID 4837PiperazineHCID 6995101N,N'-Diacetyl-L-cystine

Produkt 1

HCID 131718840HCID 131718840, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 962WaterLösungsmittel

Versuchsvorschrift

To N,N'-diacetyl-L-cystine (4.60 mmole, 1.49 g) dissolved in 5 mL of water was added piperazine (4.60 mmole, 0.90 g). To the solution was added enough isopropanole to cause formation of an oil, which slowly solidifies. The salt was isolated and dried. Physical data: Mp >170° C. (dec.) 1H-NMR (D2O) δ: 2.05 [6H,s,CH3 ], 2.96 [2H,dd,CH2S], 3.26 [2H,dd,CH2S], 3.42 [8H,s,CH2 (2,3,5,6)], 4.49 [2H,dd,CHN]

Aufarbeitung

  1. additionTo the solution was added enough isopropanole
  2. customThe salt was isolated
  3. customdried

Quellen und Nachweise

ORD-Eintrag
ord-d8e32015c1a74521bdc6954b216fce32
Quelldatensatz
uspto-grants-1998_10
Patentnummer
US05824681

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