Ammonium Hydroxide → HCID 86605522, Verbindung

HRID 404999Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 404999
[OH-].[NH4+:2].[N:3]([CH2:6][CH2:7][CH2:8][S:9](Cl)(=[O:11])=[O:10])=[N+:4]=[N-:5]>C(O)C>[N:3]([CH2:6][CH2:7][CH2:8][S:9]([NH2:2])(=[O:11])=[O:10])=[N+:4]=[N-:5]

Komponenten

4

Edukt 2

HCID 14923Ammonium HydroxideHCID 538209503-Azidopropane-1-sulfonyl chloride

Produkt 1

HCID 86605522HCID 86605522, VerbindungAusbeute 86 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

Ammonium hydroxide (28%) (10 mL) was added to a solution of 3-azido-1-propanesulfonyl chloride (˜2.29 g, 12.53 mmol; obtained in step 2) in ethanol (10 mL). The reaction mixture was stirred at room temperature for 3 h then concentrated. The residual material was passed through a short silica gel column using hexanes:ethyl acetate as eluent to isolate 3-azido-1-propanesulfonamide (1.5 g, 86%).

Aufarbeitung

  1. concentrationthen concentrated

Quellen und Nachweise

ORD-Eintrag
ord-44f2ef1886bf4c5a910a7febca11a14d
Quelldatensatz
uspto-grants-2014_06
Patentnummer
US08748656B2

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