Methylamine → HCID 178462848, Verbindung

HRID 40761

Reaktionsgleichung

Reaktionsgleichung von HRID 40761
[C:1]1(=[O:17])[N:5]([CH2:6][CH2:7][S:8](Cl)(=[O:10])=[O:9])[C:4](=[O:12])[C:3]2=[CH:13][CH:14]=[CH:15][CH:16]=[C:2]12.[CH3:18][NH2:19]>C1COCC1.O>[C:4]1(=[O:12])[N:5]([CH2:6][CH3:7])[C:1](=[O:17])[C:2]2=[CH:16][CH:15]=[CH:14][CH:13]=[C:3]12.[CH3:18][NH:19][SH:8](=[O:9])=[O:10]

Komponenten

5

Edukt 2

HCID 6329MethylamineHCID 3087392-Phthalimidoethanesulfonyl chloride

Produkt 1

HCID 178462848HCID 178462848, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 962WaterLösungsmittelHCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

2-Phthalimidoethanesulfonyl chloride (2.0 g) was added portion wise to a solution of 2.0 M methylamine in THF (15 ml) and the solution obtained this way was stirred at room temperature. After 48 hours the reaction mixture was poured in water (50 ml) causing the title compound to precipitate. The product was collected by filtration and recrystallized from EtOH:water, 50:1 to yield: 1.04 g (48%) of the desired product as a solid.

Aufarbeitung

  1. customthe solution obtained this way

Quellen und Nachweise

ORD-Eintrag
ord-15af8745e0104771a2b59e6f0ad73bcc
Quelldatensatz
uspto-grants-2013_09
Patentnummer
US08530486B2

Verknüpfte Notizen

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