3-methoxy-N-methyl-2-nitroaniline → 3-methoxy-N1-methylbenzene-1,2-diamine

HRID 408094Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 408094
[CH3:1][O:2][C:3]1[C:4]([N+:11]([O-])=O)=[C:5]([NH:9][CH3:10])[CH:6]=[CH:7][CH:8]=1>C(OCC)(=O)C.[Pd]>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][CH:6]=[C:5]([NH:9][CH3:10])[C:4]=1[NH2:11]

Komponenten

4

Edukt 1

HCID 580715913-methoxy-N-methyl-2-nitroaniline

Produkt 1

HCID 106069363-methoxy-N1-methylbenzene-1,2-diamineAusbeute 95,4 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

7.4 g (3-methoxy-2-nitrophenyl)-methylamine are suspended in 150 ml of ethyl acetate and hydrogenated with 1 g Pd/C 10% at a pressure of 50 psi and at ambient temperature. After 4.5 hours the catalyst is suction filtered and the filtrate is evaporated to dryness. 5.9 g of the product are obtained as an oil.

Aufarbeitung

  1. filtrationsuction filtered
  2. customthe filtrate is evaporated to dryness

Quellen und Nachweise

ORD-Eintrag
ord-55e2faf7537d4f5d9580a088716d65b6
Quelldatensatz
uspto-grants-2014_06
Patentnummer
US08759326B2

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