1-Naphthol → 1-Dichlorophosphoryloxynaphthalene

HRID 408959Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 408959
[P:1]([Cl:5])(Cl)([Cl:3])=[O:2].[C:6]1([OH:16])[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH:9]=[CH:8][CH:7]=1.C(N(CC)CC)C>C(OCC)C>[P:1]([Cl:5])([Cl:3])(=[O:2])[O:16][C:6]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH:9]=[CH:8][CH:7]=1

Komponenten

5

Edukt 3

HCID 70051-NaphtholHCID 8471TriethylamineHCID 24813Phosphorus oxychloride

Produkt 1

HCID 5756311-DichlorophosphoryloxynaphthaleneAusbeute 90 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 3283Diethyl EtherLösungsmittel

Versuchsvorschrift

Phosphorus oxychloride (1.94 mL, 1 equiv) and α-naphthol (Aldrich, 3 g, 1 equiv) were stirred in anhydrous diethyl ether (20 mL). Anhydrous triethylamine was added (2.90 mL, 1 equiv) at −78° C. and the solution was allowed to warm to room temperature after 25 min. The triethylamine hydrochloride salt was filtered off and the solvent was removed under reduced pressure to give a clear pale yellow oil (4.88 g, 90%).

Aufarbeitung

  1. filtrationThe triethylamine hydrochloride salt was filtered off
  2. customthe solvent was removed under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-60fb9df45ea44f87932f011862e456c1
Quelldatensatz
uspto-grants-2014_06
Patentnummer
US08759318B2

Notizen zur Reaktion

Wird geladen…