HCID 17925871, Verbindung → 4-CarboxyMethyl-cyclohexanecarboxylic acid ethyl ester

HRID 410030Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 410030
[CH2:1]([O:3][C:4]([CH:6]1[CH2:11][CH2:10][C:9](=[CH:12][C:13]([OH:15])=[O:14])[CH2:8][CH2:7]1)=[O:5])[CH3:2]>CCO.[Pd]>[CH2:1]([O:3][C:4]([CH:6]1[CH2:11][CH2:10][CH:9]([CH2:12][C:13]([OH:15])=[O:14])[CH2:8][CH2:7]1)=[O:5])[CH3:2]

Komponenten

4

Edukt 1

HCID 17925871HCID 17925871, Verbindung

Produkt 1

HCID 158961924-CarboxyMethyl-cyclohexanecarboxylic acid ethyl esterAusbeute 42 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

To a solution of 2-(4-(ethoxycarbonyl)cyclohexylidene)acetic acid (6.0 g, 28.3 mmol) in EtOH (50 ml) was slowly added 10% Pd/C (306 mg). The solution was hydrogenated overnight. The catalyst was filtered off. The filtrate was concentrated in vacuo to afford 2.5 g of product as colorless oil (42%).

Aufarbeitung

  1. filtrationThe catalyst was filtered off
  2. concentrationThe filtrate was concentrated in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-884459c38d28486abf5c93ec89e88205
Quelldatensatz
uspto-grants-2014_06
Patentnummer
US08759548B2

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