N-methyl-4-(methylamino)-3-nitrobenzamide → 3-amino-N-methyl-4-(methylamino)benzamide

HRID 410717Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 410717
[CH3:1][NH:2][C:3](=[O:15])[C:4]1[CH:9]=[CH:8][C:7]([NH:10][CH3:11])=[C:6]([N+:12]([O-])=O)[CH:5]=1>[Pd]>[NH2:12][C:6]1[CH:5]=[C:4]([CH:9]=[CH:8][C:7]=1[NH:10][CH3:11])[C:3]([NH:2][CH3:1])=[O:15]

Komponenten

3

Edukt 1

HCID 40234001N-methyl-4-(methylamino)-3-nitrobenzamide

Produkt 1

HCID 463444453-amino-N-methyl-4-(methylamino)benzamideAusbeute 100,4 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 23938PalladiumKatalysator

Versuchsvorschrift

3-Amino-N-methyl-4-methylamino-benzamide (460 mg) was prepared by following General Procedure B starting from N-methyl-4-methylamino-3-nitro-benzamide (535 mg) and Pd/C (10% by weight, 54 mg). The crude product was used in the next step without further purification.

Aufarbeitung

  1. customThe crude product was used in the next step without further purification

Quellen und Nachweise

ORD-Eintrag
ord-cb980d97b02f44e09c954a7e21e5ccdb
Quelldatensatz
uspto-grants-2014_06
Patentnummer
US08759535B2

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