Methyl 4-(methylamino)-3-nitrobenzoate → Methyl 3-amino-4-(methylamino)benzoate

HRID 410720

Reaktionsgleichung

Reaktionsgleichung von HRID 410720
[CH3:1][O:2][C:3](=[O:15])[C:4]1[CH:9]=[CH:8][C:7]([NH:10][CH3:11])=[C:6]([N+:12]([O-])=O)[CH:5]=1>[Pd]>[CH3:1][O:2][C:3](=[O:15])[C:4]1[CH:9]=[CH:8][C:7]([NH:10][CH3:11])=[C:6]([NH2:12])[CH:5]=1

Komponenten

3

Edukt 1

HCID 7650848Methyl 4-(methylamino)-3-nitrobenzoate

Produkt 1

HCID 15586064Methyl 3-amino-4-(methylamino)benzoateAusbeute 96,1 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 23938PalladiumKatalysator

Versuchsvorschrift

3-amino-4-methylamino-benzoic acid methyl ester (677 mg) was prepared by following General Procedure B starting from 4-methylamino-3-nitro-benzoic acid methyl ester (822 mg) and Pd/C (10% by weight, 82 mg). The crude product was used in the next step without further purification.

Aufarbeitung

  1. customThe crude product was used in the next step without further purification

Quellen und Nachweise

ORD-Eintrag
ord-c0c7b5facc1644408fce75264afc20cd
Quelldatensatz
uspto-grants-2014_06
Patentnummer
US08759535B2

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