2-Diethylamino-4-methylamino-5-nitro-benzoic acid methyl ester → 5-Amino-2-diethylamino-4-methylamino-benzoic acid methyl ester

HRID 410793Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 410793
[CH3:1][O:2][C:3](=[O:20])[C:4]1[CH:9]=[C:8]([N+:10]([O-])=O)[C:7]([NH:13][CH3:14])=[CH:6][C:5]=1[N:15]([CH2:18][CH3:19])[CH2:16][CH3:17]>[Pd]>[CH3:1][O:2][C:3](=[O:20])[C:4]1[CH:9]=[C:8]([NH2:10])[C:7]([NH:13][CH3:14])=[CH:6][C:5]=1[N:15]([CH2:16][CH3:17])[CH2:18][CH3:19]

Komponenten

3

Edukt 1

HCID 673332942-Diethylamino-4-methylamino-5-nitro-benzoic acid methyl ester

Produkt 1

HCID 673331485-Amino-2-diethylamino-4-methylamino-benzoic acid methyl esterAusbeute 94,7 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 23938PalladiumKatalysator

Versuchsvorschrift

5-Amino-2-diethylamino-4-methylamino-benzoic acid methyl ester (1.015 g) was prepared by following General Procedure B starting from 2-diethylamino-4-methylamino-5-nitro-benzoic acid methyl ester (1.2 g) and Pd/C (10% by weight, 120 mg). The crude product was used in the next step without further purification.

Aufarbeitung

  1. customThe crude product was used in the next step without further purification

Quellen und Nachweise

ORD-Eintrag
ord-81cb3ae7de1243119d98e156d43280b1
Quelldatensatz
uspto-grants-2014_06
Patentnummer
US08759535B2

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