3,3-Dimethoxy-4-benzyloxycarbonylamino-tetrahydrofuran → 3,3-Dimethoxy4-amino-tetrahydrofuran

HRID 413231Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 413231
[CH3:1][O:2][C:3]1([O:19][CH3:20])[CH:7]([NH:8]C(OCC2C=CC=CC=2)=O)[CH2:6][O:5][CH2:4]1>[Pd].C(O)C>[CH3:1][O:2][C:3]1([O:19][CH3:20])[CH:7]([NH2:8])[CH2:6][O:5][CH2:4]1

Komponenten

4

Edukt 1

HCID 185234863,3-Dimethoxy-4-benzyloxycarbonylamino-tetrahydrofuran

Produkt 1

HCID 185234873,3-Dimethoxy4-amino-tetrahydrofuran

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

A mixture of 3,3-Dimethoxy4-benzyloxycarbonylamino-tetrahydrofuran (16 g, 57 mmol) and 10% palladium on charcoal (2 g) in ethanol (200 ml) was stirred under an atmosphere of hydrogen (50 psi) for 12 h. The mixture was filtered and concentrated to afford the title compound as a yellow oil, 8 g, 100%.

Aufarbeitung

  1. filtrationThe mixture was filtered
  2. concentrationconcentrated

Quellen und Nachweise

ORD-Eintrag
ord-ddca4aa2d4c2416d9a5c942fdeeb5746
Quelldatensatz
uspto-grants-2003_05
Patentnummer
US06566373B2

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