HCID 58455289, Verbindung → 1,3-Dihydroxypropan-2-yl phenyl succinate

HRID 41827Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 41827
[C:1]([O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)(=[O:19])[CH2:2][CH2:3][C:4]([O:6][CH:7]1[CH2:12][O:11]C(C2C=CC=CC=2)[O:9][CH2:8]1)=[O:5]>C(O)C.[Pd]>[C:4]([O:6][CH:7]([CH2:12][OH:11])[CH2:8][OH:9])(=[O:5])[CH2:3][CH2:2][C:1]([O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)=[O:19]

Komponenten

4

Edukt 1

HCID 58455289HCID 58455289, Verbindung

Produkt 1

HCID 584552561,3-Dihydroxypropan-2-yl phenyl succinate

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

Phenyl 2-phenyl-1,3-dioxan-5-yl succinate (0.11 g, 0.3 mmol) was dissolved in ethanol (20 ml) under argon and Pd/C (0.09 g, 0.1 mmol) was added. The flask was flushed with hydrogen and allowed to stir under 1 atm H2 at room temperature for 16 h. The crude reaction mixture was passed through a plug of celite and the solvent was removed under reduced pressure yielding (0.9 g, 0.26 mmol, 89%). The product was used without any further purification.

Aufarbeitung

  1. customThe flask was flushed with hydrogen
  2. customThe crude reaction mixture
  3. customthe solvent was removed under reduced pressure
  4. customyielding (0.9 g, 0.26 mmol, 89%)
  5. customThe product was used without any further purification

Quellen und Nachweise

ORD-Eintrag
ord-3c4db04d025a4a348b07f1c720ab1e55
Quelldatensatz
uspto-grants-2013_09
Patentnummer
US08535655B2

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