4-(4-Methylpiperazin-1-yl)benzoic acid → N-(4-chloro-3-(4-(4-methylpiperazin-1-yl)benzamido)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	4-(4-Methylpiperazin-1-yl)benzoic acid	HCID 736532	—
Edukt	N-(3-amino-4-chlorophenyl)-2-methyl-6-(trifluoromethyl)nicotinamide	HCID 16730560	—
Produkt	N-(4-chloro-3-(4-(4-methylpiperazin-1-yl)benzamido)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide	HCID 16730714	—

Reaktionsschritte

N-(3-amino-4-chlorophenyl)-2-methyl-6-(trifluoromethyl)nicotinamide (0.15 mmol) was used in general procedure 2 with 4-(4-methylpiperazin-1-yl)benzoic acid (0.167 mmol). The product was purified by RP-HPLC to give N-(4-chloro-3-(4-(4-methylpiperazin-1-yl)benzamido)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide. MS (Q1) 532.0 (M)+

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08101610B2
Quelldatensatz	uspto-grants-2012_01
ORD ID	ord-a3bfcaa7085843a3bb302caec3b4a782
Quellennotiz	uspto-grants-2012_01