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HRID421678

反应详情

EQUATION

反应方程式

HRID 421678 的结构方程式

REACTANTS

反应物

2
结构：CN1CCN(c2ccc(C(=O)O)cc2)CC1
HCID736532

4-(4-methylpiperazin-1-yl)benzoic acid

C12H16N2O2

结构：Cc1nc(C(F)(F)F)ccc1C(=O)Nc1ccc(Cl)c(N)c1
HCID16730560

未命名化合物

PRODUCTS

生成物

1
结构：Cc1nc(C(F)(F)F)ccc1C(=O)Nc1ccc(Cl)c(NC(=O)c2ccc(N3CCN(C)CC3)cc2)c1
HCID16730714

未命名化合物

PROCEDURE

实验过程

N-(3-amino-4-chlorophenyl)-2-methyl-6-(trifluoromethyl)nicotinamide (0.15 mmol) was used in general procedure 2 with 4-(4-methylpiperazin-1-yl)benzoic acid (0.167 mmol). The product was purified by RP-HPLC to give N-(4-chloro-3-(4-(4-methylpiperazin-1-yl)benzamido)phenyl)-2-methyl-6-(trifluoromethyl)nicotinamide. MS (Q1) 532.0 (M)+

WORKUP

后处理

  1. customThe product was purified by RP-HPLC