HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-(3-Amino-1,2,4-oxadiazol-5-yl)-1-azabicyclo(2.2.1)heptane → HCID 86086918, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-(3-Amino-1,2,4-oxadiazol-5-yl)-1-azabicyclo(2.2.1)heptane | HCID 163938 | — |
| Edukt | 3-Chloro-n'-hydroxy-2-methylbenzidine | HCID 87101445 | — |
| Produkt | HCID 86086918 | HCID 86086918 | 46% |
Reaktionsschritte
According to the general protocol for oxadiazole synthesis described in Example 40(C) the conversion of 3-chloro-N′-hydroxy-2-methylbenzidine (628 mg, 3.4 mmol) afforded 387 mg of 5-(but-3-ynyl)-3-(3-chloro-2-methylphenyl)-1,2,4-oxadiazole (Yield: 46%) as yellow oil.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08101637B2 |
| Quelldatensatz | uspto-grants-2012_01 |
| ORD ID | ord-4feea008220d476d99fb328136536254 |
| Quellennotiz | uspto-grants-2012_01 |