Sodium Sulfite → Sodium 5-bromo-2-methoxybenzenesulfinate

HRID 42355Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 42355
[O-]S([O-])=O.[Na+:5].[Na+].C([O-])(O)=O.[Na+].[Br:12][C:13]1[CH:14]=[CH:15][C:16]([O:23][CH3:24])=[C:17]([S:19](Cl)(=[O:21])=[O:20])[CH:18]=1>O.O1CCOCC1>[Br:12][C:13]1[CH:14]=[CH:15][C:16]([O:23][CH3:24])=[C:17]([S:19]([O-:21])=[O:20])[CH:18]=1.[Na+:5]

Komponenten

6

Edukt 3

HCID 24437Sodium SulfiteHCID 516892Sodium BicarbonateHCID 5200205-Bromo-2-methoxybenzene-1-sulfonyl chloride

Produkt 1

HCID 67162120Sodium 5-bromo-2-methoxybenzenesulfinate

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 962WaterLösungsmittelHCID 312751,4-DioxaneLösungsmittel

Reaktionsbedingungen

Temperatur
70 °C

Versuchsvorschrift

To a solution of Na2SO3 (1.42 g) and NaHCO3 (0.948 g) in H2O (17 ml) at 70° C. was added a solution of 5-bromo-2-methoxybenzene-1-sulfonyl chloride (2 g) in dioxane (17 ml) dropwise. The reaction mixture was stirred at 70° C. for 80 minutes and cooled to room temperature. The solvent was removed under vacuum to yield sodium 5-bromo-2-methoxybenzenesulfinate as white solid. The solid was placed under high vacuum overnight and used without further purification.

Aufarbeitung

  1. temperaturecooled to room temperature
  2. customThe solvent was removed under vacuum

Quellen und Nachweise

ORD-Eintrag
ord-af953d32c592450796c85f7988a72c99
Quelldatensatz
uspto-grants-2013_09
Patentnummer
US08536187B2

Notizen zur Reaktion

Wird geladen…