4-Nitroisophthalic acid → 4-Aminobenzene-1,3-dioic acid

HRID 425761

Reaktionsgleichung

Reaktionsgleichung von HRID 425761
[N+:1]([C:4]1[CH:12]=[CH:11][C:7]([C:8]([OH:10])=[O:9])=[CH:6][C:5]=1[C:13]([OH:15])=[O:14])([O-])=O>CO.[Pd]>[NH2:1][C:4]1[CH:12]=[CH:11][C:7]([C:8]([OH:10])=[O:9])=[CH:6][C:5]=1[C:13]([OH:15])=[O:14]

Komponenten

4

Edukt 1

HCID 30624384-Nitroisophthalic acid

Produkt 1

HCID 113558524-Aminobenzene-1,3-dioic acidAusbeute 87 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

To a solution of 4-nitro isophthalic acid (98 g, 0.457 mol) in methanol (5 L) was added Pd/C (20%) and hydrogenated at RT for 4 h. The reaction mixture was filtered through celite and filtrate concentrated under vacuum to give 4-amino isophthalic acid (72 g, 87%) as a solid.

Aufarbeitung

  1. filtrationThe reaction mixture was filtered through celite and filtrate
  2. concentrationconcentrated under vacuum

Quellen und Nachweise

ORD-Eintrag
ord-cfbdf63e2ce043f4bfa7dd3fb1708429
Quelldatensatz
uspto-grants-2012_01
Patentnummer
US08106214B2

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