Benzylamine → N-Benzyl-4-chloropyridin-2-amine

Temperatur

80 °C

palladium(II) acetate (0.018 g, 0.08 mmol), (R)-(-)-1-[(S)-2-(DICYCLOHEXYLPHOSPHINO)FERROCENYL]ETHYLDI-T-BUTYLPHOSPHINE (0.066 g, 0.12 mmol), sodium tert-butoxide (0.194 g, 2.02 mmol), phenylmethanamine (0.110 mL, 1.01 mmol) and 2,4-dichloropyridine (0.151 mL, 1.01 mmol) were suspended in DME (4 mL) and sealed into a microwave tube. The reaction was heated to 80 °C for 30 minutes in the microwave reactor and cooled to RT.

ORD-Eintrag

ord-db5f6efbde1f4ab4bc3688dd8d2a4d0e

Quelldatensatz

750 AstraZeneca ELN dataset

Originallink

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