Acetonitrile → 3-(4-(Acryloyloxy)butoxy)-2-hydroxypropyl 2-benzoylbenzoate

HRID 42733

Reaktionsgleichung

Reaktionsgleichung von HRID 42733
[C:1]([C:9]1[CH:17]=[CH:16][CH:15]=[CH:14][C:10]=1[C:11]([OH:13])=[O:12])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(#N)C.C([C:25]1C=C(C)C=[C:27](C(C)(C)C)[C:26]=1[OH:36])(C)(C)C.[OH:37][CH2:38][CH2:39][CH2:40][CH2:41][O:42][C:43](=[O:46])[CH:44]=[CH2:45].C(OCC1OC1)C1OC1>[Br-].C([N+](CCCC)(CCCC)CCCC)CCC.CC(N(C)C)=O>[C:43]([O:42][CH2:41][CH2:40][CH2:39][CH2:38][O:37][CH2:25][CH:26]([OH:36])[CH2:27][O:12][C:11](=[O:13])[C:10]1[CH:14]=[CH:15][CH:16]=[CH:17][C:9]=1[C:1](=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1)(=[O:46])[CH:44]=[CH2:45]

Komponenten

7

Edukt 4

HCID 6342AcetonitrileHCID 68132-Benzoylbenzoic AcidHCID 314042,6-Di-tert-butyl-4-methylphenolHCID 223231504-Hydroxybutylacrylate glycidylether

Produkt 1

HCID 583255113-(4-(Acryloyloxy)butoxy)-2-hydroxypropyl 2-benzoylbenzoate

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 74236Tetrabutylammonium BromideKatalysatorHCID 31374DimethylacetamideLösungsmittel

Versuchsvorschrift

A reaction mixture containing 2-benzoyl benzoic acid (40.0 g, 0.1722 mol), acetonitrile (300 mL), dimethylacetamide (10 mL), tetrabutylammonium bromide (5.6 g, 17.22 mmol) and 2,6-di-tert-butyl-4-methylphenol (0.3 g, 1.4 mmol) was heated to reflux. At this temperature 4-hydroxybutylacrylate glycidylether (28.0 g, 140 mmol) was added and the mixture was allowed to stir at reflux temperature for 16 hours.

Aufarbeitung

  1. temperaturewas heated to reflux
  2. temperatureat reflux temperature for 16 hours

Quellen und Nachweise

ORD-Eintrag
ord-320c13860a99488e881a36e355cfd6ef
Quelldatensatz
uspto-grants-2013_09
Patentnummer
US08536217B2

Verknüpfte Notizen

Wird geladen…