Sodium borohydride → (2-Isopropyl-6-methylphenyl)methanol
Reaktionsgleichung
[CH:1]([C:4]1[CH:11]=[CH:10][CH:9]=[C:8]([CH3:12])[C:5]=1[CH:6]=[O:7])([CH3:3])[CH3:2].[BH4-].[Na+]>CO>[CH:1]([C:4]1[CH:11]=[CH:10][CH:9]=[C:8]([CH3:12])[C:5]=1[CH2:6][OH:7])([CH3:3])[CH3:2]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
To a solution of 2-isopropyl-6-methylbenzaldehyd (1.75 g, 10.8 mmol) in methanol (15 ml) was added sodium borohydride (0.35 g, 9.5 mmol) and the mixture was stirred 1 h. at room temperature. The solvent was evaporated under reduced pressure and to the residue was added hexane and water. The organic layer was separated and evaporated under reduced pressure to give 1.73 g (98%) of the title compound as an oil.
Aufarbeitung
- customThe solvent was evaporated under reduced pressure and to the residue
- additionwas added hexane and water
- customThe organic layer was separated
- customevaporated under reduced pressure
Quellen und Nachweise
- ORD-Eintrag
- ord-e446b94faa7448ce83e2e8534874030c
- Quelldatensatz
- uspto-grants-2001_11
- Patentnummer
- US06313137B1
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