Hydrochloric Acid → (2,6-Dichlorophenyl)methanesulfonamide

HRID 429245

Reaktionsgleichung

[Cl:1][C:2]1[CH:12]=[CH:11][CH:10]=[C:9]([Cl:13])[C:3]=1[CH2:4][S:5](Cl)(=[O:7])=[O:6].Cl.[OH-].[NH4+:16]>>[Cl:1][C:2]1[CH:12]=[CH:11][CH:10]=[C:9]([Cl:13])[C:3]=1[CH2:4][S:5]([NH2:16])(=[O:7])=[O:6]

Komponenten

Edukt 3

HCID 313Hydrochloric Acid

HCID 14923Ammonium Hydroxide

HCID 594465(2,6-Dichlorophenyl)methanesulfonyl chloride

Produkt 1

HCID 13631936(2,6-Dichlorophenyl)methanesulfonamideAusbeute 64 %

Versuchsvorschrift

The 2,6-dichlorobenzylsulfonylchloride (27 g, 103.6 mmol) in ammonium hydroxide (270 ml) was stirred at room temperature for 3 hours. On acidification with cooled concentrated hydrochloric acid a precipitate separated and was filtered to give desired product (16 g, 64%) MS(EI) m/e 239 (M−).

Aufarbeitung

customseparated
filtrationwas filtered

Quellen und Nachweise

ORD-Eintrag: ord-0cca67bc26fc480983a683f2d36302d8
Quelldatensatz: uspto-grants-2001_11
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US06316478B1

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