Oxalyl chloride → 3-Cyano-2,4,5-trifluoro-benzoyl chloride

HRID 430593Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 430593
[C:1]([C:3]1[C:4]([F:14])=[C:5]([CH:9]=[C:10]([F:13])[C:11]=1[F:12])[C:6](O)=[O:7])#[N:2].C(Cl)(=O)C([Cl:18])=O>CN(C)C=O.C(Cl)Cl>[C:1]([C:3]1[C:4]([F:14])=[C:5]([CH:9]=[C:10]([F:13])[C:11]=1[F:12])[C:6]([Cl:18])=[O:7])#[N:2]

Komponenten

5

Edukt 2

HCID 65578Oxalyl chlorideHCID 18417533195532-64-0

Produkt 1

HCID 186187613-Cyano-2,4,5-trifluoro-benzoyl chloride

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 6228DimethylformamideKatalysatorHCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

111 g of 3-cyano-2,4,5-trifluoro-benzoic acid, 84 g of oxalyl chloride and a few drops of dimethylformamide in 930 ml of dry methylene chloride are stirred at room temperature for 5 hours. The reaction mixture is concentrated by evaporation and the residue is distilled in vacuo.

Aufarbeitung

  1. concentrationThe reaction mixture is concentrated by evaporation
  2. distillationthe residue is distilled in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-2b89adf6c891449e8baa063d8a6962d8
Quelldatensatz
uspto-grants-2001_11
Patentnummer
US06323213B1

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