Thiophenol → 3,4-Bis(4-methoxyphenyl)-6-(phenylthio)pyridazine

HRID 432621Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 432621
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[N:10]=[N:11][C:12](Cl)=[CH:13][C:14]=2[C:15]2[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=2)=[CH:5][CH:4]=1.[C:24]1([SH:30])[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[N:10]=[N:11][C:12]([S:30][C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=3)=[CH:13][C:14]=2[C:15]2[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=2)=[CH:5][CH:4]=1

Komponenten

3

Edukt 2

HCID 7969ThiophenolHCID 125680843,4-Bis(4-methoxyphenyl)-6-chloropyridazine

Produkt 1

HCID 187600273,4-Bis(4-methoxyphenyl)-6-(phenylthio)pyridazine

Versuchsvorschrift

In a similar manner as in Example 2, 3,4-bis(4-methoxyphenyl)-6-chloropyridazine (352.5 mg, 1.08 mmol) and thiophenol were reacted as starting materials at 100° C. for 7 hours and post-treatment was then conducted, whereby the title compound was obtained as a colorless crystalline powder (55.8 mg, 12.9%). Melting point: 176.9-177.8° C. (chloroform-diethyl ether)

Aufarbeitung

  1. customat 100° C.
  2. customfor 7 hours

Quellen und Nachweise

ORD-Eintrag
ord-63c8129050654dc8a0d3be6916740a6e
Quelldatensatz
uspto-grants-2003_12
Patentnummer
US06664256B1

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