Phenylacetone → 1-Phenyl-2-propanol

HRID 434370

Reaktionsgleichung

Reaktionsgleichung von HRID 434370
[BH4-].[Na+].[C:3]1([CH2:9][C:10](=[O:12])[CH3:11])[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1>CO>[C:3]1([CH2:9][CH:10]([OH:12])[CH3:11])[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

Komponenten

4

Edukt 2

HCID 7678PhenylacetoneHCID 4311764Sodium borohydride

Produkt 1

HCID 941851-Phenyl-2-propanolAusbeute 86,7 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

Sodium borohydride (10.0 g) was added portionwise to an ice cold stirred solution of 1-phenylpropan-2-one (30.0 g) in methanol (500 ml). The mixture was stirred for 4 hours, evaporated and partitioned between water (100 ml) and chloroform (200 ml). The organic phase was dried (MgSO4) and evaporated to give the product as a colourless oil (26.4 g).

Aufarbeitung

  1. customevaporated
  2. custompartitioned between water (100 ml) and chloroform (200 ml)
  3. dry with materialThe organic phase was dried (MgSO4)
  4. customevaporated

Quellen und Nachweise

ORD-Eintrag
ord-e0ce0ce0e0664f128aefe1478c6790fe
Quelldatensatz
uspto-grants-1983_08
Patentnummer
US04396627

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