Aniline → N-phenylcarbamoyl chloride

HRID 434530

Reaktionsgleichung

Reaktionsgleichung von HRID 434530
[C:1]([Cl:4])(Cl)=[O:2].[NH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1>C1(C)C=CC=CC=1>[C:6]1([NH:5][C:1]([Cl:4])=[O:2])[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1

Komponenten

4

Edukt 2

HCID 6115AnilineHCID 6371Phosgene

Produkt 1

HCID 576741N-phenylcarbamoyl chloride

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

The intermediate is then reacted with a secondary amine in an aprotic solvent such as toluene at temperatures from room temperature or below up to the boiling point of the solvent. An example of this process is the reaction of phosgene with aniline to yield the intermediate N-(phenyl)carbamyl chloride which is then reacted with N-benzyl-n-butylamine to yield 1-benzyl-1-(n-butyl)-3-(phenyl)urea.

Quellen und Nachweise

ORD-Eintrag
ord-e87810831aea4dcca6a2fde26a49ebcc
Quelldatensatz
uspto-grants-1983_08
Patentnummer
US04397868

Verknüpfte Notizen

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