Potassium Cyanide → 3-Methyl-6-(phenylthio)-phenylacetonitrile

HRID 435666Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 435666
[C-:1]#[N:2].[K+].[CH3:4][C:5]1[CH:6]=[C:7]([C:10]([S:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[CH:11][CH:12]=1)[CH2:8]Cl>O.C(O)C>[CH3:4][C:5]1[CH:6]=[C:7]([CH2:8][C:1]#[N:2])[C:10]([S:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[CH:11][CH:12]=1

Komponenten

5

Edukt 2

HCID 9032Potassium CyanideHCID 125391003-Methyl-6-(phenylthio)-benzyl chloride

Produkt 1

HCID 125391013-Methyl-6-(phenylthio)-phenylacetonitrile

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 702EthanolLösungsmittelHCID 962WaterLösungsmittel

Versuchsvorschrift

194 g of potassium cyanide in 250 ml of water are heated under reflux for 17 hours under an argon atmosphere with 616.9 g of 3-methyl-6-(phenylthio)-benzyl chloride in 900 ml of ethanol. Then the ethanol is distilled off under reduced pressure, the residue then diluted with water and extracted with ether. The extracts are washed with water, dried over sodium sulphate and evaporated. There is obtained 3-methyl-6-(phenylthio)-phenylacetonitrile as an oil.

Aufarbeitung

  1. distillationThen the ethanol is distilled off under reduced pressure
  2. additionthe residue then diluted with water
  3. extractionextracted with ether
  4. washThe extracts are washed with water
  5. dry with materialdried over sodium sulphate
  6. customevaporated

Quellen und Nachweise

ORD-Eintrag
ord-0e7610fd672145cb80db885400d10957
Quelldatensatz
uspto-grants-1977_02
Patentnummer
US04006144

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