Salicyloyl chloride → HCID 178513857, Verbindung

HRID 435735

Reaktionsgleichung

Reaktionsgleichung von HRID 435735
[Na+].[NH:2]1[CH:6]=[N:5][C:4]([C:7]([NH-:9])=[O:8])=[N:3]1.[C:10](Cl)(=[O:18])[C:11]1[C:12](=[CH:14][CH:15]=[CH:16][CH:17]=1)[OH:13]>C(#N)C>[C:10]([C:6]1[NH:2][N:3]=[C:4]([C:7]([NH2:9])=[O:8])[N:5]=1)(=[O:18])[C:11]1[C:12](=[CH:14][CH:15]=[CH:16][CH:17]=1)[OH:13]

Komponenten

4

Edukt 2

HCID 74041Salicyloyl chlorideHCID 178514233HCID 178514233, Verbindung

Produkt 1

HCID 178513857HCID 178513857, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6342AcetonitrileLösungsmittel

Versuchsvorschrift

A 25 ml. portion of dry acetonitrile is added to a mixture of 1.3 g. of the s-triazole carboxamide sodium salt and 2 g. of salicyloyl chloride followed by a few pellets of 4A molecular sieves. The mixture is stirred at room temperature for 16 hours and then filtered through Celite. The colorless solid is obtained on evaporating the filtrate is washed with diethyl ether; yield, 1 g., m.p. 147°-150° C. (dec.). Its infrared spectrum is essentially the same as that obtained from the product in Example 7.

Aufarbeitung

  1. filtrationfiltered through Celite
  2. customThe colorless solid is obtained
  3. customon evaporating the filtrate
  4. washis washed with diethyl ether
  5. customyield
  6. customthat obtained from the product in Example 7

Quellen und Nachweise

ORD-Eintrag
ord-fc5a8c5d9c524162bb776eeae08319f4
Quelldatensatz
uspto-grants-1977_02
Patentnummer
US04006159

Verknüpfte Notizen

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