N-(4-nitrophenyl)pentanamide → N-(4-aminophenyl)pentanamide

HRID 435809Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 435809
[N+:1]([C:4]1[CH:16]=[CH:15][C:7]([NH:8][C:9](=[O:14])[CH2:10][CH2:11][CH2:12][CH3:13])=[CH:6][CH:5]=1)([O-])=O>C(O)C.[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([NH:8][C:9](=[O:14])[CH2:10][CH2:11][CH2:12][CH3:13])=[CH:15][CH:16]=1

Komponenten

4

Edukt 1

HCID 3762929N-(4-nitrophenyl)pentanamide

Produkt 1

HCID 1725711N-(4-aminophenyl)pentanamide

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 23938PalladiumKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

A solution of 4'-nitrovaleranilide (13.33 g., 0.06 mole) in absolute ethanol (750 ml.) is hydrogenated over 10% palladium on charcoal (2 g.) until the theoretical absorption is achieved. The catalyst is removed and the solvent is removed in vacuo. The residue is recrystallized from butyl chloride to yield 9.0 g., m.p. 81°-83° C.

Aufarbeitung

  1. customThe catalyst is removed
  2. customthe solvent is removed in vacuo
  3. customThe residue is recrystallized from butyl chloride
  4. customto yield 9.0 g

Quellen und Nachweise

ORD-Eintrag
ord-8c20ac76b3604360b3c9fcffec14b3fe
Quelldatensatz
uspto-grants-1977_02
Patentnummer
US04006233

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