Hydrochloric Acid → HCID 21430453, Verbindung

Reaktionsgleichung

[CH3:1][N:2]([CH2:16][C:17]1[O:18][CH:19]=[CH:20][CH:21]=1)[C:3](=[O:15])[C:4]1[CH:9]=[CH:8][C:7](Cl)=[C:6]([S:11](=[O:14])(=[O:13])[NH2:12])[CH:5]=1.[CH3:22][N:23]1[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]1.Cl>O>[CH3:1][N:2]([CH2:16][C:17]1[O:18][CH:19]=[CH:20][CH:21]=1)[C:3](=[O:15])[C:4]1[CH:9]=[CH:8][C:7]([N:26]2[CH2:27][CH2:28][N:23]([CH3:22])[CH2:24][CH2:25]2)=[C:6]([S:11](=[O:14])(=[O:13])[NH2:12])[CH:5]=1

Komponenten

Versuchsvorschrift

103 Grams of 4-chloro-3-sulfamoylbenzoic acid-N-methyl-2-furylmethylamide (0.3 mole) were heated under reflux with 0.3 l of N-methylpiperazine for 5 hours. After the reaction solution had been poured into 2 l of water, the pH value of the mixture was adjusted to 8.0 with 5N HCl. After standing at room temperature for 3 days, the separated yellow resin had crystallized. The reaction product was suction-filtered, washed thoroughly with water and was recrystallized from a mixture of methanol and water.